%0 Journal Article %K Indoor environment department %K Indoor Air Quality (IAQ) %K Sick building syndrome (SBS) %K Building-related symptoms %K Commercial Building Ventilation and Indoor Environmental Quality Group %K HVAC system %K Indoor environmental quality (IEQ) %A Mark J Mendell %A Quanhong Lei-Gomez %A Anna G Mirer %A Olli Seppänen %A Gregory Brunner %B Indoor Air %D 2008 %G eng %P 1.2, 1.7 %T Risk factors in heating, ventilating, and air-conditioning systems for occupant symptoms in U.S. office buildings: the U.S. EPA BASE study %U https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0668.2008.00531.x %V 18 %2 LBNL-61870 %8 08/07/2008 %X
Building-related symptoms in office workers worldwide are common, but of uncertain etiology. One cause may be contaminants related to characteristics of heating, ventilating, and air-conditioning (HVAC) systems. We analyzed data from 97 representative air-conditioned U.S. office buildings in the Building Assessment and Survey Evaluation (BASE) study. Using logistic regression models with generalized estimating equations, we estimated odds ratios (OR) and 95% confidence intervals (CI) for associations between building-related symptom outcomes and HVAC characteristics. Outdoor air intakes less than 60 m above ground were associated with significant increases in most symptoms: e.g., for upper respiratory symptoms, OR for intake heights 30 to 60 m, 0 to