%0 Conference Paper
%K Sick building syndrome (SBS)
%K Ventilation
%K Carbon dioxide
%K BASE study
%K Logistic regression
%A Christine A Erdmann
%A Kate C Steiner
%A Michael G Apte
%B Indoor Air 2002, June 30 - July 5, 2002
%C Monterey, CA
%D 2002
%G eng
%P 443-448
%T Indoor Carbon Dioxide Concentrations and Sick Building Syndrome Symptoms in the Base Study Revisited: Analyses of the 100 Building Dataset
%V 3
%2 LBNL-49584
%X <p>In previously published analyses of the 41-building 1994-1996 USEPA Building Assessment Survey and Evaluation (BASE) dataset, higher workday time-averaged indoor minus outdoor CO<sub>2</sub> concentrations (dCO<sub>2</sub>) were associated with increased prevalence of certain mucous membrane and lower respiratory sick building syndrome (SBS) symptoms, even at peak dCO<sub>2</sub> concentrations below 1,000 ppm. For this paper, similar analyses were performed using the larger 100-building 1994-1998 BASE dataset. Multivariate logistic regression analyses quantified the associations between dCO<sub>2</sub> and the SBS symptoms, adjusting for age, sex, smoking status, presence of carpet in workspace, thermal exposure, relative humidity, and a marker for entrained automobile exhaust. Adjusted dCO<sub>2</sub> prevalence odds ratios for sore throat and wheeze were 1.17 and 1.20 per 100-ppm increase in dCO<sub>2</sub> (p &lt;0.05), respectively. These new analyses generally support our prior findings. Regional differences in climate, building design, and operation may account for some of the differences observed in analyses of the two datasets.</p>