Transitioning to a bioeconomy that makes use of low-emission and waste feedstocks requires greater flexibility to accommodate seasonal variations and mitigate long-term storage challenges, such as material loss and fire risk. To achieve this goal, biomass deconstruction technologies must efficiently handle diverse feedstocks. Here, we assess the cost of using butylamine─a distillable solvent─to deconstruct 22 different biomass feedstocks: 7 herbaceous, 9 woody, 4 food processing residues, and 2 blends. Lignocellulosic sugar production costs, based on current empirical data, range from $1.3 to 6.1/kg, suggesting that substantial improvements are required to compete with conventional sugars. The high solvent loading (850 g/kg of whole slurry) is a process bottleneck. Lowering the solvent loading to 59 g/kg of whole slurry, demonstrated in an L-scale reactor using poplar biomass, reduces the minimum sugar selling price by 33%. Solvent loading and recovery, solid loading, sugar yield, enzyme use, and delivered biomass cost all play key roles in reaching sugar production costs of $0.45–0.79/kg. Strategic feedstock blending to maximize carbohydrate content, process optimization to improve conversion efficiency, and the selection of low-cost feedstocks are important to advancing feedstock-flexible biorefineries.
BT - ACS Sustainable Chemistry & Engineering DA - 18/08/2025 DO - 10.1021/acssuschemeng.5c05029 IS - 32 N2 -Transitioning to a bioeconomy that makes use of low-emission and waste feedstocks requires greater flexibility to accommodate seasonal variations and mitigate long-term storage challenges, such as material loss and fire risk. To achieve this goal, biomass deconstruction technologies must efficiently handle diverse feedstocks. Here, we assess the cost of using butylamine─a distillable solvent─to deconstruct 22 different biomass feedstocks: 7 herbaceous, 9 woody, 4 food processing residues, and 2 blends. Lignocellulosic sugar production costs, based on current empirical data, range from $1.3 to 6.1/kg, suggesting that substantial improvements are required to compete with conventional sugars. The high solvent loading (850 g/kg of whole slurry) is a process bottleneck. Lowering the solvent loading to 59 g/kg of whole slurry, demonstrated in an L-scale reactor using poplar biomass, reduces the minimum sugar selling price by 33%. Solvent loading and recovery, solid loading, sugar yield, enzyme use, and delivered biomass cost all play key roles in reaching sugar production costs of $0.45–0.79/kg. Strategic feedstock blending to maximize carbohydrate content, process optimization to improve conversion efficiency, and the selection of low-cost feedstocks are important to advancing feedstock-flexible biorefineries.
PB - American Chemical Society (ACS) PY - 2025 SP - 13100 EP - 13111 T2 - ACS Sustainable Chemistry & Engineering TI - Cost of Deconstruction Depots for Diversified, Waste-Based Lignocellulosic Sugars Using Distillable Solvents UR - https://doi.org/10.1021/acssuschemeng.5c05029 VL - 13 SN - 2168-0485, 2168-0485 ER -