TY - JOUR KW - Exposure KW - Cumulative exposure KW - Biomarkers KW - Nicotine KW - Secondhand smoke KW - Policy KW - Aggregate exposures KW - Housing KW - Tobacco smoke AU - Georg E Matt AU - Penelope J. E Quintana AU - Hugo Destaillats AU - Lara A Gundel AU - Mohamad Sleiman AU - Brett C Singer AU - Peyton Jacob III AU - Neal L Benowitz AU - Jonathan P Winickoff AU - Virender Rehan AU - Prue Talbot AU - Suzaynn F Schick AU - Jonathan M Samet AU - Yinisheng Wang AU - Bo Hang AU - Manuela Martins-Green AU - James F Pankow AU - Melbourne F Hovell AB -
Background: While there is broad consensus regarding the health impact of tobacco use and secondhand smoke exposure, considerable ambiguity exists about the nature and consequences of thirdhand smoke (THS). Objectives: We introduce definitions of THS and THS exposure and review recent findings about (a) constituents, indoor sorption-desorption dynamics, and transformations of THS, (b) distribution and persistence of THS in residential settings, (c) implications for pathways of exposure, (d) potential clinical significance and health effects, and (e) behavioral and policy issues that affect and are affected by THS. Discussion: Physical and chemical transformations of tobacco smoke pollutants take place over timescales ranging from seconds to months and include the creation of secondary pollutants (e.g., tobacco-specific nitrosamines). THS persists in real-world residential settings in the air, dust, and surfaces, and is associated with elevated levels of nicotine on hands and nicotine in urine of nonsmokers residing in former smoker homes. Much still needs to be learned about the chemistry, exposure, toxicology, health risks, and policy implications.
Conclusion: The existing evidence provides strong support for pursuing a programmatic research agenda on THS to close gaps in our current understanding of the chemistry, exposure, toxicology, health effects, as well as behavioral, economic, and socio-cultural considerations and consequences of THS. Such a research agenda is necessary to illuminate the role of THS in existing and future tobacco control efforts to decrease smoking initiation and smoking levels, to increase cessation attempts and sustained cessation, and to reduce the cumulative effects of tobacco use on morbidity and mortality.
BT - Environmental Health Perspectives DA - 01/10/2011 DO - 10.1289/ehp.1103500 N2 -Background: While there is broad consensus regarding the health impact of tobacco use and secondhand smoke exposure, considerable ambiguity exists about the nature and consequences of thirdhand smoke (THS). Objectives: We introduce definitions of THS and THS exposure and review recent findings about (a) constituents, indoor sorption-desorption dynamics, and transformations of THS, (b) distribution and persistence of THS in residential settings, (c) implications for pathways of exposure, (d) potential clinical significance and health effects, and (e) behavioral and policy issues that affect and are affected by THS. Discussion: Physical and chemical transformations of tobacco smoke pollutants take place over timescales ranging from seconds to months and include the creation of secondary pollutants (e.g., tobacco-specific nitrosamines). THS persists in real-world residential settings in the air, dust, and surfaces, and is associated with elevated levels of nicotine on hands and nicotine in urine of nonsmokers residing in former smoker homes. Much still needs to be learned about the chemistry, exposure, toxicology, health risks, and policy implications.
Conclusion: The existing evidence provides strong support for pursuing a programmatic research agenda on THS to close gaps in our current understanding of the chemistry, exposure, toxicology, health effects, as well as behavioral, economic, and socio-cultural considerations and consequences of THS. Such a research agenda is necessary to illuminate the role of THS in existing and future tobacco control efforts to decrease smoking initiation and smoking levels, to increase cessation attempts and sustained cessation, and to reduce the cumulative effects of tobacco use on morbidity and mortality.
PY - 2011 SP - 1218 EP - 1226 T2 - Environmental Health Perspectives TI - Thirdhand Tobacco Smoke: Emerging Evidence and Arguments for a Multidisciplinary Research Agenda VL - 119 ER -