@article{11037,
  author = {Deanna L Dowdy and Thomas E McKone and Dennis P.H Hsieh},
  title = {The Use of the Molecular Connectivity Index for Estimating Biotransfer Factors},
  abstract = {<p><span class="searchTerm0">Biotransfer factors</span> (BTFs) represent the ratio of the concentration of a chemical found in animal tissues such as beef or milk to the animal{\textquoteright}s daily intake of that chemical. <span class="searchTerm0">Using</span> currently available citations for BTFs in meat and milk, the <span class="searchTerm0">use</span> of <span class="searchTerm0">molecular connectivity indices</span> (MCIs) as a quantitative structure-activity relationship (QSAR) for predicting the BTFs for organic chemicals is evaluated. Based on a statistical evaluation of correlation, residual error, and cross validation, this evaluation reveals that the MCI provides both higher reliability and a fast and cost-effective method for predicting the potential <span class="searchTerm0">biotransfer</span> of a chemical from environmental media into food. When compared to the <span class="searchTerm0">use</span> of <em>K</em><sub>ow</sub> as a predictor of BTFs, the analysis here indicates that MCI can substantially increase the reliability with which BTFs can be <span class="searchTerm0">estimated</span>.</p>},
  year = {1996},
  booktitle = {Environmental Science \& Technology},
  journal = {Environmental Science \& Technology},
  series = {Environmental Science \& Technology},
  volume = {30},
  pages = {984-989},
  month = {02/1996},
  doi = {10.1021/es950398c},
  language = {eng},
}